by Master832 » Thu Jul 24, 2008 9:32 pm
by pukalo » Sun Jul 27, 2008 10:23 pm
by guitarhero » Mon Jul 28, 2008 11:05 pm
pukalo wrote:Although its been said that binaural beats will not affect your health or anything like that but who knows. Overuse of anything can get you sick or make you messed up. Be careful and dont overdo it!
by Master832 » Wed Jul 30, 2008 10:57 pm
by RasmusTheRaver » Thu Jul 31, 2008 8:30 am
by guitarhero » Mon Aug 04, 2008 11:03 pm
Epinephrine is synthesized from norepinephrine in a synthetic pathway shared by all catecholamines, including L-dopa, dopamine, norepinephrine, and epinephrine.
Epinephrine is synthesized via methylation of the primary distal amine of norepinephrine by phenylethanolamine N-methyltransferase (PNMT) in the cytosol of adrenergic neurons and cells of the adrenal medulla (so-called chromaffin cells). PNMT is only found in the cytosol of cells of adrenal medullary cells. PNMT uses S-adenosylmethionine (SAMe) as a cofactor to donate the methyl group to norepinephrine, creating epinephrine.
For norepinephrine to be acted upon by PNMT in the cytosol, it must first be shipped out of granules of the chromaffin cells. This may occur via the catecholamine-H+ exchanger VMAT1. VMAT1 is also responsible for transporting newly synthesized epinephrine from the cytosol back into chromaffin granules in preparation for release.
Adrenochrome or Andrenichrome is a made up drug by Hunter S Thompson used in the book and movie Fear and Loathing in Las Vegas.
Near end of this film, Duke takes too much "andrenichrome" and has a nasty experience. Andrenichrome was a substance that Hunter S. Thompson made up for the book when he originally wrote it, and was kept in the script by Terry Gilliam. After showing a rough cut of the film to a test audience, Gilliam was approached by a group of young men, one of which complimented him on the film in general, but said that his favorite scene was the andrenichrome scene. He said that he had used the drug and that Gilliam had captured the effects perfectly. Gilliam didn't have the heart to tell the kid that it was made up, and went along with his story.
by guitarhero » Mon Aug 04, 2008 11:15 pm